@article{90296,
  author = {Monica Skoge and Sahin Naqvi and Yigal Meir and Ned Wingreen},
  title = {Chemical Sensing by Nonequilibrium Cooperative Receptors.},
  abstract = { Cooperativity arising from local interactions in equilibrium receptor systems provides gain, but does not increase sensory performance, as measured by the signal-to-noise ratio (SNR) due to a fundamental tradeoff between gain and intrinsic noise. Here we allow sensing to be a nonequilibrium process and show that energy dissipation cannot circumvent the fundamental tradeoff, so that the SNR is still optimal for independent receptors. For systems requiring high gain, nonequilibrium 2D-coupled receptors maximize the SNR, revealing a new design principle for biological sensors. },
  year = {2013},
  journal = {Phys Rev Lett},
  volume = {110},
  month = {06/2013},
  issn = {1079-7114},
  doi = {10.1103/PhysRevLett.110.},
  language = {eng},
}