@article{200881,
  author = {Pierre Ronceray and Yaojun Zhang and Xichong Liu and Ned Wingreen},
  title = {Stoichiometry Controls the Dynamics of Liquid Condensates of Associative Proteins.},
  abstract = {<p>Multivalent associative proteins with strong complementary interactions play a crucial role in phase separation of intracellular liquid condensates. We study the internal dynamics of such "bond-network" condensates comprising two complementary proteins via scaling analysis and molecular dynamics. We find that when stoichiometry is balanced, relaxation slows down dramatically due to a scarcity of alternative binding partners following bond breakage. This microscopic slow-down strongly affects the bulk diffusivity, viscosity, and mixing, which provides a means to experimentally test this prediction.</p>
},
  year = {2022},
  journal = {Physical review letters},
  volume = {128},
  pages = {038102},
  month = {01/2022},
  issn = {1079-7114},
  doi = {10.1103/PhysRevLett.128.038102},
  language = {eng},
}